TRPM8 antagonists

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专利权人:

Dompé S.P.A.

发明人:

Alessio Moriconi,Gianluca Bianchini,Sandro Colagioia,Laura Brandolini,Andrea Aramini,Chiara Liberati,Silvia Bovolenta

申请号：

US14366796

公开号：

US09585875B2

申请日:

2012.12.19

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The invention relates to compounds acting as selective antagonists of Transient Receptor Potential cation channel subfamily M member 8 (TRPM8), and having formula (I). Said compounds are useful in the treatment of diseases associated with activity of TRPM8 such as pain, inflammation, ischaemia, neurodegeneration, stroke, psychiatric disorders, itch, irritable bowel diseases, cold induced and/or exhacerbated respiratory disorders and urological disorders.

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