novel heteroaryl and heterocycle compounds, compositions and methods abstract the invention relates to novel heteroaryl and heterocycle compounds of formula i-1, i-2 or i-3 and pharmaceutical compositions comprising them, uses and methods thereof for inhibiting the activity of pi3k and for treating inflammatory and autoimmune diseases and cancer. ************************** Translation of the abstract patent summary: "heteroaryl and heterocycle compounds, compositions and methods". The invention relates to novel heteroaryl and heterocycle compounds of formula I-1, I-2 or I-3 and pharmaceutical compositions comprising them, uses and methods thereof to inhibit pi3k activity and to treat inflammatory and autoimmune diseases. and cancer. 1/1novel heteroaryl and heterocycle compounds, compositions and methods abstract the invention relates to novel heteroaryl and heterocycle compounds of formula i-1, i-2 or i-3 and pharmaceutical compositions comprising them, uses and methods thereof for inhibiting the activity of pi3k and for treating inflammatory and autoimmune diseases and cancer. ************************** tradução do resumo resumo patente de invenção: "compostos de heteroarila e heterociclo, composições e métodos". a invenção refere-se a novos compostos de heteroarila e heterociclo de fórmula i-1, i-2 ou i-3 e composições farmacêuticas compreendendo-os, usos e métodos dos mesmos para inibir a atividade de pi3k e para tratar doenças inflamatórias e autoimunes e câncer. 1/1