The present invention relates to amylin peptide carrying nanoparticles particularly for use in medicine and includes methods for treatment of disorders e.g. of blood glucose regulation. Nanoparticle composition comprise a nanoparticle comprising a core comprising a metal and/or a semiconductor and a corona comprising a plurality of ligands covalently linked to the core wherein said ligands comprise glutathione and at least one amylin peptide that is non covalently bound to the corona.