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Combination of selected analgesics with COX II inhibitors
专利权人:
Grünenthal GmbH
发明人:
SCHIENE, Klaus,HAASE, Günter,KÖGEL, Babette-Yvonne,FRIDERICHS, Elmar,JAHNEL, Ulrich
申请号:
ES03775368
公开号:
ES2640404T3
申请日:
2003.11.18
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
Combination of active ingredients formed by at least one analgesic compound A and at least one COX II inhibitor, characterized in that the COX II inhibitor is selected from celecoxib or rofecoxib, compound A being selected from: (1R, 2R hydrochloride) -3- (3-dimethylamino-1-ethyl-2- methylpropyl) phenol and (1S, 2S) -3- (3-dimethylamino-1-ethyl-2-methylpropyl) phenol hydrochloride, as represented or in form of their acids or bases, or in the form of their salts, in particular of physiologically tolerable salts, or in the form of their solvates, in particular of hydrates.Combinación de principios activos formada por al menos un compuesto A analgésico y al menos un inhibidor de la COX II, caracterizada porque el inhibidor de la COX II se selecciona entre celecoxib o rofecoxib, seleccionándose el compuesto A entre: clorhidrato de (1R,2R)-3-(3-dimetilamino-1-etil-2- metilpropil)fenol y clorhidrato de (1S,2S)-3-(3-dimetilamino-1-etil-2-metilpropil)fenol, en la forma representada o en forma de sus ácidos o sus bases, o en forma de sus sales, en particular de sales fisiológicamente tolerables, o en forma de sus solvatos, en particular de hidratos.
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