DINARELLO, CHARLES A.,KIM, SOO-HYUN,BUFLER, PHILIP
申请号：
CA2500577
公开号：
CA2500577C
申请日:
2003.10.03
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to the use of a cytokine-1, preferably from theIL-1 family more preferably IL-1F7b, or an isoform, mutein, fused protein,functional derivative or fragment thereof, capable of binding to IL-18 BP or amutein, fused protein, functional derivative or fragment thereof and capableof inhibiting a receptor of a cytokine-2, cytokine-2 being a member of the IL-1 family, preferably IL-18, in the manufacture of a medicament for thetreatment or prevention of a disease which is caused or aggravated by inducingsaid receptor of cytokine-2.
