SOLID DOSAGE FORMS OF (S)-ETHYL 2-AMINO-3-(4-(2-AMINO-6-((R)-1-(4-CHLORO-2-(3-METHYL-1H-PYRAZOL-1-YL)PHENYL)-2,2,2-TRIFLUOROETHOXY)PYRIMIDIN-4-YL)PHENYL)PROPANOATE
Jinling CHEN;Richard J. HOLL;Matthew S. DEAVER;Kalyan NUGURU
发明人:
Jinling CHEN,Matthew S. DEAVER,Richard J. HOLL,Kalyan NUGURU
申请号:
US13652527
公开号:
US20130172376A1
申请日:
2012.10.16
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Solid pharmaceutical dosage forms comprising (S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate (telotristat) are disclosed, as well as methods of making them and compositions useful in their manufacture.