Compounds derived from 1h indole - il - 4 - methyl - (benzofusionado heterocycle)； Composition and Pharmaceutical Combination； and use in the treatment of a disorder mediated by complement Activation or the alternative route of the same.
ADAMS CHRISTOPHER MICHAEL,BABU, CHARLES,CAPPARELLI, MICHAEL PAUL,DING JIAN,EHARA TAKERU,JENDZA KEITH,KARKI RAJESHRI GANESH,KAWANAMI TOSHIO,XUE LIANG,MAINOLFI NELLO,POWERS JAMES J.,SERRANO-WU MICHAEL H
申请号：
CL2014002919
公开号：
CL2014002919A1
申请日:
2014.10.28
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
The present invention provides a compound of formula I: (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.<；p>；COMPUESTOS DERIVADOS DE 1H-INDOL-4-IL-METIL-(HETEROCICLO BENZOFUSIONADO)； COMPOSICIÓ；N Y COMBINACIÓ；N FARMACÉ；UTICA； Y USO EN EL TRATAMIENTO DE UN TRASTORNO MEDIADO POR LA ACTIVACIÓ；N DEL COMPLEMENTO O LA RUTA ALTERNATIVA DEL MISMO QUE COMPRENDE DEGENERACIÓ；N MACULAR, RETINOPATÍ；A DIABÉ；TICA, ENFERMEDAD DE PARKINSON, ATEROSCLEROSIS, ASMA, ALERGIA, OBESIDAD.<；/p>；
