Godfrin, Yann,Bourgeaux, Vanessa,Gay, Fabien,Cortese, Thomas
申请号：
AU2015217045
公开号：
AU2015217045B2
申请日:
2015.02.12
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The invention relates to a pharmaceutical composition containing a PLP-dependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a phosphate or non-phosphate precursor of PLP, its use as a drug, its production method and a therapeutic treatment method related to it. The pharmaceutical composition comprises erythrocytes and a pharmaceutically acceptable vehicle, the erythrocytes encapsulating the PLP-dependent enzyme. The PLP-dependent enzyme may be methioninase, tyrosine phenol-lyase, tyrosine aminotransferase or cystathionine beta-synthase.
