DÉRIVÉS 5-[(PIPÉRAZIN-1-YL)-3-OXO-PROPYL]-IMIDAZOLIDINE-2,4-DIONE EN TANT QU'INHIBITEURS D'ADAMTS POUR LE TRAITEMENT DE L'OSTÉOARTHRIT

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专利权人:

Les Laboratoires Servier;Galapagos N.V.

发明人:

申请号：

EP19154886.6

公开号：

EP3575294A1

申请日:

2015.12.18

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The present invention discloses compounds according to formula I:Wherein R1, R2, R3a, R3b, and Cy are as defined herein.The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and the compounds of formula I for use in methods of treatment and for use in methods of prophylaxis and/or treatment of inflammatory conditions, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis.

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