CHENG, JYA WEI,程家维,程家維,YU, HUI YUAN,游辉元,游輝元,CHENG, HIS TSUNG,郑锡聪,鄭錫聰
申请号:
TW102143445
公开号:
TW201520231A
申请日:
2013.11.28
申请国别(地区):
TW
年份:
2015
代理人:
摘要:
The present invention provides an antimicrobial peptide, wherein the amino terminal and/or carboxyl terminal of the peptide is linked with at least one artificial bulkyl amino acid to increase the salt resistance and protease resistance of the antimicrobial peptide. The antimicrobial peptide of the invention has a high salt resistance, a high protease resistance, and a low hemolytic activity, simultaneously.一種抗微生物胜肽,其中在胜肽的胺基及/或羧基端具有至少一人工巨大胺基酸(bulkyl amino acid),以增加抗微生物胜肽的鹽類耐受性及蛋白酶耐受性。本發明之高鹽類耐受性之抗微生物胜肽具有高鹽類耐受性、高蛋白酶耐受性、以及低溶血性。