Philippe Marc Helene Dehottay,Michael Lanero Fidalgo,Dominique Janssens,Marc Roger Fernand Orval
申请号:
US14408415
公开号:
US20150166948A1
申请日:
2013.06.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to improved processes for culturing bacteria, in particular to processes for perfusion suspension culturing of bacteria in a fermenter, wherein the culture medium including the bacteria is circulated over a separation system in alternating tangential flow, wherein the separation system removes a filtrate containing inhibitory metabolites from the culture medium.