The Board of Trustees of the Leland Stanford Junior University
发明人:
Ting Liu,Daniel L. Rubin
申请号:
US15821703
公开号:
US20180143199A1
申请日:
2017.11.22
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides methods to predict the treatment response of brain tumors such as glioblastoma multiforme to anti-angiogenic therapy based on quantitative perfusion-weighted MRI that can optionally be combined with intra-tumor specific molecular profiling. Since only a subset of brain cancer patients will benefit from anti-angiogenic therapy, identification of this subset is critical so that the effectiveness of the patient's current anti-cancer treatment regimen and the patient's survival likelihood can be increased by the inclusion of an anti-angiogenic agent.