The present invention relates to pyrazole compounds of formula (Ia) or (Ib) and pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Y1, Y2, Y3, Y4, Y5, Z, R1, R2, n and R3 have one of the meanings as indicated in the specification and claims, to their use as medicaments, to pharmaceutical formulations containing said compounds and to pharmaceutical formulations said compounds in combination with one or more active substances.本發明係關於如式(Ia)或(Ib)之吡唑化合物及其醫藥可接受鹽,其中Ra、Rb、Rc、Rd、Y1、Y2、Y3、Y4、Y5、Z、R1、R2、n及R3具有如說明書及專利申請範圍中所指明含義中之一者;其等作為藥劑之用途,含有該等化合物之醫藥調配物及含有該等化合物與一或多種活性物質之組合之醫藥調配物。