The toothbrush sanitizer is a small device that can sanitize the head of a toothbrush, and includes a small steam chamber that is accessibly via sealed opening. The sealed opening is adjacent the small chamber and includes a rubber seal that opens upon entrance of a toothbrush head therein. A heating element is positioned between a water reservoir and the small chamber. The heating element is responsible for forming steam and directing said steam onto the toothbrush head located in the small steam chamber. The toothbrush sanitizer is powered by batteries or includes an electrical plug that extends from a rear surface to plug the device into an electrical outlet.