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Peptide constructs derived from the GP120 C5 domain and GP41 transmembrane domain
专利权人:
Maja Sommerfelt Grønvold
发明人:
Maja Sommerfelt Grønvold,Angus Dalgleish,Einar Tønnes Lange,Jens Olof Holmberg,Per Bengtsson,Birger Sørensen
申请号:
US13382137
公开号:
US09200065B2
申请日:
2010.07.03
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed is a method for treatment of HIV related diseases comprising targeting complexes between on the one hand the C5 domain of gp120 and on the other hand gp41 or the C2 domain of gp120. The complexes may be stabilised by administering compounds, such as antibodies, capable of directly interacting with and stabilising the complex, or by immunizing with C5 and gp41/C2 derived material so as to induce antibodies that bind to and stabilise the complex.
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