PROBLEM TO BE SOLVED: To provide an ophthalmic formulation.SOLUTION: The ophthalmic formulation includes one or a plurality of active agents that act to optimize pupil light reflex while minimizing, or effectively eliminating, any undesired eye redness in response to application thereof. The active agent includes, for example, an &alpha1 antagonist, such as an &alpha1a selective antagonist.COPYRIGHT: (C)2012,JPO&INPIT【課題】眼科製剤を提供する。【解決手段】この眼科製剤は、その適用に応じて任意の望ましくない眼充血を最小にしながら、又は効果的に排除しながら、瞳孔の対光反射を最適化するように作用する1種又は複数の有効薬剤を含む。この有効薬剤は、例えば、α1a選択的拮抗薬などのα1拮抗薬を含む。【選択図】なし