Institut National de la Santé et de la Recherche Médicale (INSERM);Centre National de la Recherche Scientifique (C.N.R.S.);Universite Nice Sophia Antipolis
发明人:
申请号：
EP13763241.0
公开号：
EP2900820B1
申请日:
2013.09.16
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The present invention relates to an in vitro or ex vivo method for producing a population of pancreatic beta-cells, comprising the step of inhibiting the expression or the activity of Arx in a population of pancreatic alpha-cells. The present invention also relates to method for inducing the conversion of pancreatic alpha-cells in pancreatic beta-cells in a patient in need thereof.
