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SKIN EXTERNAL COMPOSITION
专利权人:
发明人:
孙启发,孫啟發,LI, PO-CHI,李柏齐,李柏齊
申请号:
TW105122832
公开号:
TW201803547A
申请日:
2016.07.20
申请国别(地区):
TW
年份:
2018
代理人:
摘要:
A skin external composition is provided.  The composition includes an allotrope of carbon with surface modification, a base agent and an excipient.  The allotrope of carbon with surface modification has sp2 structure and C:O ratio thereof is 15:1 to 6:1.  The allotrope of carbon with surface modification is able to inhibit melanin formation and has reduction ability for melanin.  The cell survival rate test result of the allotrope of carbon with surface modification is more than 80%.  When 0.1% to 5% aqueous solution of the allotrope of carbon with surface modification is prepared, the absorbance is 1.5 to 2 at a wavelength of 200 nm to 400 nm.  A content of the allotrope of carbon with surface modification is 0.01 wt% to 5 wt%, a content of the base agent is 20 wt% to 60 wt% and a content of the excipient is 5 wt% to 25 wt%, based on a total weight of the skin external composition.本發明提供一種皮膚外用組成物,包括經表面改質之碳的同素異形體、基劑以及賦型劑。經表面改質之碳的同素異形體具有sp2結構且C:O比例為25:1至8:1,能夠抑制黑色素形成並對黑色素具有還原能力,且細胞存活率測試結果為80%以上的細胞存活率。當經表面改質之碳的同素異形體配製成0.1%至5%的水溶液時,在200 nm至400 nm波長下的吸光值(Absorbance)為1.5至2。以皮膚外用組成物的總重量計,經表面改質之碳的同素異形體的含量為0.01 wt%至5 wt%,基劑的含量為20 wt%至60 wt%,賦型劑的含量為5 wt%至25 wt%。無
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