DINSMORE, CHRISTOPHER J.,JEWELL, JAMES P.,KATZ, JASON D.,MACHACEK, MICHELLE R.,OTTE, RYAN D.,YOUNG, JONATHAN R.,DINSMORE CHRISTOPHER J.,JEWELL JAMES P.,KATZ JASON D.,MACHACEK MICHELLE R.,OTTE RYAN D.,YOUNG JONATHAN R.,YOUNG
申请号:
PL06785319
公开号:
PL1896422T3
申请日:
2006.06.22
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.