HENRIK C. HANSEN,GREGORY S. WAGNER,SARAH C. ATTWELL,KEVIN G. MCLURE,EWELINA B. KULIKOWSKI
申请号：
PT10714825
公开号：
PT2421533T
申请日:
2010.04.21
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
Disclosed are methods of regulating interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1) and methods of treating and/or preventing cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s) by administering a naturally occurring or synthetic quinazolone derivative. The invention provides novel synthetic quinazolone compounds, as well as pharmaceutical compositions comprising those compounds.
