A medical manipulator system that includes a joint, a first sensor that detects an amount of rotational motion of the joint, an actuator that drives the joint via a wire, a second sensor that detects an amount of operation of the actuator based on a rotation angle of the actuator, an input device, and a controller. The controller generates a control signal based on: an operation mode in which the control signal is generated by a transfer function that receives an input target value of the rotation angle of the joint and the amount of operation of the actuator, and a calibration mode in which the transfer function is adjusted based on comparing to a predetermined threshold value the amount of rotational motion of the joint and the amount of operation of the actuator. The controller then transmits the generated control signal to the actuator to drive the joint.
