Lars BÄRFACKER,Gerhard SIEMEISTER,Tobias HEINRICH,Stefan PRECHTL,Detlef STÖCKIGT,Antje ROTTMANN
申请号：
US15115274
公开号：
US20170334899A1
申请日:
2015.01.26
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to amino-substituted isothiazoles of general formula (I): in which A, R1 and R2 are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.
