PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
ALLIAN, Ayman D.,JAYANTH, Jayanthy,MOHAMED, Mohamed-Eslam F.,MULHERN, Mathew M.,NORDSTROEM, Lars F.,OTHMAN, Ahmed A.,ROZEMA, Michael J.,BHAGAVATULA, Lakshmi,MARROUM, Patrick J.,MAYER, Peter T.,SHEIKH,
申请号：
SG11201802990R
公开号：
SG11201802990RA
申请日:
2016.10.17
申请国别(地区):
SG
年份:
2018
代理人:
摘要：
The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.
