Catherine Elisabeth Charron,David Michel Adrien Taddei,John Underwood,Jonathan Gareth Williams,Kazuhiro Ito,Peter John Murray,Peter Strong,Simon Christopher Hirst,Stuart Thomas Onions,William Garth Ra
申请号:
BRPI0922962
公开号:
BRPI0922962A2
申请日:
2009.12.11
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
The present disclosure relates to compounds of formula (I): which are inhibitors of p38 mitogen-activated protein kinase enzymes, particularly the alpha and gamma kinase sub-types thereof, and their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD.