KUHNE, MICHELLE,BRAMS, PETER,TANAMACHI, DAWN, M,KORMAN, ALAN,CARDARELLI, JOSEPHINE M
申请号:
NZ57592407
公开号:
NZ575924A
申请日:
2007.10.01
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Provided are CXCR4 antibodies with specified amino acid sequences and their variants, which can inhibit binding of SDF-1 to human CXCR4 and inhibit capillary tube formation by human umbilical vein endothelial cells. The antibodies are useful for inhibiting growth or metastasis of tumour cells and for inhibition angiogenesis.