PROBLEM TO BE SOLVED: To provide an ultrasonic diagnostic apparatus capable of easily and precisely performing echo measurement and light intensity measurement by minimizing influence of an organic deformation during measurement while securing accuracy in a relative relationship of each unit of an optical probe and an ultrasonic probe, and a biological examination apparatus.SOLUTION: An ultrasonic diagnostic apparatus has an ultrasonic probe 12, an image generating unit, an optical probe 40, an integration solid-state image sensor 403a and analysis means 424. The optical probe 40 has at least one first light emission means 400a for emitting light of an absorption wavelength band of a biogenic substance from the periphery of an ultrasonic wave sending/receiving surface towards the inside of a subject, and a plurality of optical detection parts 401a and 401b for detecting the intensity of light of a specific wavelength emitted from at least the one first light emission means 400a and diffused and reflected in the inside of the subject. The analysis means 424 analyzes a variation of the light intensity detected by each of the optical detection part 401a and 401b.SELECTED DRAWING: Figure 2COPYRIGHT: (C)2016,JPO&INPIT【課題】光プローブ及び超音波プローブの各ユニットの相対位置精度を確保しつつ、測定時の生体変形の影響を最小化して、簡便かつ精度良くにエコー測定と光強度測定を行うことができる超音波診断装置及び生体検査装置を提供する。【解決手段】超音波診断装置は、超音波プローブ12と、画像生成ユニットと、光プローブ40と、集積化固体撮像素子403aと、解析手段424と、を具備する。光プローブ40は、超音波送受信面の周囲から被検体の内部に向けて生体成分の吸収波長帯である光を照射する少なくとも一つの第1光照射手段400aと、少なくとも一つの第1光照射手段400aから照射され被検体内で拡散反射された特定波長の光の強度を検出する複数の光検出部401a,401bと、を有する。解析手段424は、各光検出部401a,401bで検出された光強度の変化を解析する。【選択図】図2