Charles Hague;Michel Claude Vellard;Vish Koppaka;Melita Dvorak-Ewell;Erno Pungor
发明人:
Michel Claude Vellard,Vish Koppaka,Melita Dvorak-Ewell,Erno Pungor,Charles Hague
申请号：
US12355453
公开号：
US08128925B2
申请日:
2009.01.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
