A wound treatment includes a guiding unit and a negative pressure collecting module. The guiding unit includes a main body, an elastic member and an accommodating portion formed within the elastic member. The main body has a first end is communicated to the wound, and a second end. The elastic member is disposed in the main body to isolate the first end from the second end. The negative pressure collecting module, connecting with the guiding unit, includes a negative pressure source providing negative pressure to the wound, and a collecting device collecting exudates of the wound. When the negative pressure source sucks air from the guiding unit, the elastic member deforms, and the accommodating portion communicates with the first end and the second end, respectively. When the negative pressure source stops sucking, the elastic member is restored, and the accommodating portion isolates the first end from the second end.
