The present disclosure relates to RSV F protein mutants, nucleic acids or vectors encoding a RSV F protein mutant, compositions comprising a RSV F protein mutant or nucleic acid, and uses of the RSV F protein mutants, nucleic acids or vectors, and compositions.本發明係關於RSV F蛋白突變體、編碼RSV F蛋白突變體之核酸或載體、包含RSV F蛋白突變體或核酸之組合物,及該等RSV F蛋白突變體、核酸或載體及組合物之用途。