The present invention discloses quinoline compounds, a preparation method thereof and a use thereof as a urate transporter inhibitor drug. The compounds and salts, hydrates or solvates provided in the present invention, as a selective uric acid reabsorption inhibitor, can be used in the treatment of hyperuricemia and gout by promoting uric acid to excrete from the body and reducing serum uric acid, and have the effect of reducing the uric acid in the animal body and human body.
