John BYRD,Amy JOHNSON,Gerard LOZANSKI,Arletta LOZANSKI,Jennifer WOYACH
申请号:
US15516088
公开号:
US20170298446A1
申请日:
2015.10.05
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Biomarkers and methods are disclosed that identify patients being treated with a BTK inhibitor that have acquired a mutation that will cause resistance to the BTK inhibitor. Therefore, also disclosed is a method for treating a hematological cancer in the patient that involves detecting an acquired mutation that causes resistance to a BTK inhibitor and then selecting an alternative treatment if resistance is detected.