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iPS cell-derived vascular progenitor cell sheet and method for producing the same
专利权人:
国立大学法人名古屋大学
发明人:
室原 豊明,本多 裕之,柴田 玲,石井 正和,鬼頭 哲太郎,鈴木 博彦
申请号:
JP2013542997
公开号:
JP6048839B2
申请日:
2012.11.07
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
The present invention addresses the problem of providing a vascular progenitor cell sheet derived from induced pluripotent stem cells, which has the strength to tolerate practical applications and exhibits a high treatment effect. This vascular progenitor cell sheet derived from induced pluripotent stem cells is prepared by performing: (1) a step for preparing magnetically labeled Flk-1 positive cells derived from induced pluripotent stem cells; (2) a step for preparing a mixture of the Flk-1 positive cells and a gel material including type I collagen, laminin, type IV collagen and entactin as active ingredients, and then disseminating the mixture in a culture vessel; (3) a step for drawing the Flk-1 positive cells in the mixture to the culture surface of the culture vessel by application of a magnetic force to form a multi-layered cell layer; and (4) a step for gelling the gel material.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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