The present invention relates to a 3D oral acupuncture system. The 3D oral acupuncture system is for integrating areas of lips, teeth, gums, and the tongue to a 3D disease-syndrome differentiation scope. Disease information is obtained by observing organs such as lips, teeth, gums, and the tongue, which can reflect information of acupuncture points, sensitive points, disease reaction points, and organs conditions of a body. The present invention provides a method for doctors to differentiate syndromes of diseases by observing lips, teeth, gums, and the tongue separately by different systems, in order to increase the accuracy of diagnosis.本發明係為一種立體口腔微針系統,主要將嘴唇、牙齒、牙齦及舌頭、整合成一立體式疾病辨證範圍,利用嘴唇、牙齒、牙齦及舌頭各組織器官得以反應人身整體之經絡、穴位、敏感點及人體全身疾病反應點和五臟六腑之表現區,而顯現出病症資訊,提供醫者經嘴唇、牙齒、牙齦及舌頭分開觀察,由不同的系統去辨證疾病,提高正確診斷率。