Universal anti-CD22 chimeric antigen receptor engineered immune cells

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专利权人:

Cellectis SA

发明人:

Smith, Julianne,Duchateau, Philippe,Derrien, Murielle

申请号：

AU2018246377

公开号：

AU2018246377A1

申请日:

2018.03.30

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

The present invention relates to an engineered immune cell endowed with a new CD22 Chimeric Antigen Receptors (CD22 CAR) with a deletion in the TRAC gene that is able to redirect said immune cell specificity and reactivity toward selected tumor cells. The engineered immune cells endowed with such CARs are particularly suited for treating relapsed refractory CD22 expressing cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/