THOMAS JR., JAMES BARNWELL,MCNAUGHTON-SMITH, GRANT ANDREW,AMATO, GEORGE SALVATORE
申请号：
AU2003303484
公开号：
AU2003303484C1
申请日:
2003.12.23
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides quinazolinone, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders (, migraine, ataxia, Parkinson's disease, bipolar disorders, trigeminal neuralgia, spasticity, mood disorders, brain tumors, psychotic disorders, myokymia, seizures, epilepsy, hearing and vision loss, Alzheimer's disease, age-related memory loss, learning deficiencies, anxiety and motor neuron diseases) and as neuroprotective agents (, to prevent stroke and the like) by modulating potassium channels associated with the onset or recurrence of the indicated conditions.
