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CELLULE SOUCHE MÉSENCHYMATEUSE, ET COMPOSITION PHARMACEUTIQUE
专利权人:
Ltd.;Rohto Pharmaceutical Co.
发明人:
申请号:
EP18760998.7
公开号:
EP3591038A1
申请日:
2018.02.22
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The purpose of the present invention is to provide a mesenchymal stem cell that is highly safe when used as a medicine. The present invention is a mesenchymal stem cell characterized in that the Tissue Factor (TF) is expressed at low levels. Furthermore, the present invention includes a mesenchymal stem cell characterized in that at least one integrin gene selected from the group consisting of ITGA11, ITGA1, ITGB5, ITGBL1, ITGB1 and ITGAV is expressed at low levels. Furthermore, the present invention includes a mesenchymal stem cell characterized in that at least one integrin gene selected from the group consisting of ITGA4, ITGA9, ITGA7, and ITGA10 is expressed at high levels. It is preferable that the mesenchymal stem cell is allogeneic and is derived from a fatty tissue. The present invention also includes a pharmaceutical composition containing the mesenchymal stem cell.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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