Klaus LINZ,Babette-Yvonne KOEGEL,Wolfgang SCHROEDER,Thomas CHRISTOPH,Jean De VRY,Elmar FRIDERICHS
申请号：
US14732451
公开号：
US20150342929A1
申请日:
2015.06.05
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention relates to the use of compounds which exhibit an affinity for the μ-opioid receptor of at least 100 nM (Ki value, human) and an affinity for the ORL-1 receptor, wherein the ratio between the affinities ORL1/μ defined as 1/[Ki(ORL1)/Ki(μ)] is from 0.1 to 30, for the treatment of pain.
