A device for treating wounds with negative pressure is provided that includes an adhesive film that defines a chamber in relation to the wound; a vacuum source can be adjusted to produce negative pressures in the same chamber; a canister for collecting liquids drained from the wound; a reservoir containing medicated liquids to be instilled in the wound; an unit for setting both the negative pressure and the quantity of administered medication; and a pressure sensor to detect the negative pressure present in said chamber. The device further includes a spiral diffuser mounted on said film comprising a high number of protrusions on tube coils, the spiral diffuser being connected both to vacuum source and to a pump; micro-valves for diffusing medicated liquids, one for each protrusion on coiled tube of spiral diffuser; and a pump administering medicated liquids exerting a pressure capable of opening the micro-valves present in protrusions.