The invention relates to a composition that includes a first agent selected including an agent that possesses anti-inflammatory activity or acetaminophen, phenacetin, tramadol and the like; a second agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an adenosine 5-monophosphate-activated Protein kinase (AMPK) activator a third agent that possesses or maintains serotonin activity.本發明關於一種組成物,其包括選自包括擁有抗發炎活性或乙醯胺苯酚、乙醯氧乙苯胺、查馬朵等等藥劑的一第一藥劑;選自由氧化性磷酸化抑制劑、離子載體及腺苷5-單磷酸鹽-活化的蛋白激酶(AMPK)活化劑組成之群組的一第二藥劑;擁有或維持5-羥色胺活性的一第三藥劑。
