PROBLEM TO BE SOLVED: To provide an inhibiting agent for active oxygen production and fibroblast disorder due to TNF-α.SOLUTION: An inhibiting agent for active oxygen production due to TNF-α contains at least one ingredient, as an active ingredient, selected from ethyl gallate, caffeoyl glucose, methoxy caffeic acid, hypoletin 7-O-glucoside, quercetin 3-O-(6"-galloyl)-glucoside, kaempherol 3-O-glucoside, quercetin 3-O-glucoside, kaempferol3-O-(6"-galloyl)-glucoside, gossypetin, junsainosideA, quercetin, tiliroside and kaempferol. Further, an inhibiting agent for active oxygen production due to TNF-α contains an extract of Brasenia schreberi as an active ingredient.COPYRIGHT: (C)2014,JPO&INPIT【課題】TNF-αによる活性酸素産生抑制剤及びTNF-αによる線維芽細胞障害抑制剤の提供。【解決手段】Ethyl gallate,caffeoyl glucose,methoxy caffeic acid,hypoletin 7-O-glucoside,quercetin 3-O-(6"-galloyl)-glucoside,kaempherol 3-O-glucoside,quercetin 3-O-glucoside,kaempferol3-O-(6"-galloyl)-glucoside,gossypetin,junsainosideA,quercetin,tilirosideおよびkaempferolのうちの少なくとも1つを有効成分とするTNF-αによる活性酸素産生抑制剤。さらにジュンサイ抽出物を有効成分とするTNF-αによる活性酸素産生抑制剤。【選択図】なし
