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Use of ErbB3 inhibitors in the treatment of triple negative and basal-like breast cancers
专利权人:
Victor Moyo;Gabriela Garcia
发明人:
Victor Moyo,Gabriela Garcia
申请号:
US13583949
公开号:
US08895001B2
申请日:
2011.03.11
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided are methods of suppressing growth of triple negative breast tumors and basal-like breast tumors by contacting tumor cells with an ErbB3 inhibitor, e.g., an anti-ErbB3 antibody. Also provided are methods for treating triple negative breast cancer or basal-like breast cancer in a patient by administering to the patient an ErbB3 inhibitor, e.g., an anti-ErbB3 antibody. The treatment methods can further comprise selecting a patient having a triple negative breast cancer or basal-like breast cancer and then administering an ErbB3 inhibitor to the patient. The treatment methods also can further comprise administering at least one additional anti-cancer agent to the patient in combination with the ErbB3 inhibitor.
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