The Board of Trustees of the University of Illinois;The Johns Hopkins University;Vanquish Oncology, Inc.
发明人:
Paul J. HERGENROTHER,Rachel C. BOTHAM,Timothy M. FAN,Mark J. GILBERT,Michael J. Handley,Avadhut JOSHI,Gregory J. RIGGINS,Theodore M. TARASOW
申请号:
US15243860
公开号:
US20170042886A1
申请日:
2016.08.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.