An object of the present invention is to provide a preparation technology capable of suppressing yellowing of a pharmaceutical composition containing ethyl aminobenzoate and quaternary ammonium salt caused by exposure to light, so as to have excellent preparation stability. To solve the problem, when being blended with ethyl aminobenzoate and quaternary ammonium salt, a pharmaceutical composition combined and blended with one or more of polyhydric alcohol, monoterpene, polyvinyl pyrrolidone, and hydroxyethyl cellulose can be provided with an excellent preparation stability by suppressing yellowing caused by exposure to light.[課題] 本發明之目的為提供一種可在包含胺苯甲酸乙酯及四級銨鹽之醫藥組成物中抑制因暴露於光而產生的黃變,使之具備優異製劑安定性之製劑技術。 [解決手段] 在摻合胺苯甲酸乙酯及四級銨鹽的同時,組合並摻合多元醇、單萜烯、聚乙烯吡咯啶酮及羥基乙基纖維素之中的1種以上之醫藥組成物,能具備抑制因暴露於光而產生的黃變之優異製劑安定性。無