Compound 4 - [3 - (carbamoylamino) phenyl] - N - methyl - N - ciclopentil - 1h-imidazole-1-carboxamide, Modulator of FAAH Enzyme； Synthesis process； Pharmaceutical Composition and Method for Treatment or prevention of a aafeccio asocada the endocannabinoid System, such as Regulation of appetite, obesity, Anorexia, other.
ROSA CARLA PATRICIA DA COSTA PEREIRA,GUSMÄO DE NORONHA RITA,KISS LASZLO ERNO,SOARES DA SILVA PATRICIO MANUEL VIERIA ARAÚJO,RUSSO DOMENICO,WAHNON JORGE BRUNO REIS,MATON WILLIAM
申请号：
CL2015000178
公开号：
CL2015000178A1
申请日:
2015.01.23
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
A compound having the following structure: or a pharmaceutically acceptable salt or derivative thereof. The compound may be used in the treatment or prevention of a disorder selected from appetite regulation, obesity, metabolic disorders, cachexia, anorexia, pain, inflammation, neurotoxicity, neurotrauma, stroke, multiple sclerosis, spinal cord injury, Parkinson's disease, levodopa-induced dyskinesia, Huntington's disease, Gilles de la Tourette's syndrome, tardive dyskinesia, dystonia, amyotrophic lateral sclerosis, Alzheimer's disease, epilepsy, schizophrenia, anxiety, depression, insomnia, nausea, emesis, alcohol disorders, drug addictions such as opiates, nicotine, cocaine, alcohol and psychostimulants, hypertension, circulatory shock, myocardial reperfusion injury, atherosclerosis, asthma, glaucoma, retinopathy, cancer, inflammatory bowel disease, acute and chronic liver disease such as hepatitis and liver cirrhosis, arthritis and osteoporosis.<；p>；COMPUESTO HETEROCICLICO 4-[3-(CARBAMOILAMINO)FENIL]-N-CICLOPENTIL-N-METIL-1H-IMIDAZOL-1-CARBOXAMIDA, MODULADOR DE LA ENZIMA AMIDA HIDROLASA DE ACIDOS GRASOS (FAAH)； COMPOSICION FARMACEUTICA； Y USO PARA TRATAR O PREVENIR UNA AFECCION ASOCIADA AL SISTEMA ENDOCANABINOIDE, COMO REGULACION DEL APETITO, OBESIDAD, ANOREXIA, OTRAS.<；/p>；
