CORMAN, MICHAEL L.,HUNGERFORD, WILLIAM M.,GOLEBIOWSKI, ADAM,BECKETT, RAYMOND P.,MAZUR, MARZENA,OLEJNICZAK, SYLWIA,OLCZAK, JACEK
申请号：
CA2937147
公开号：
CA2937147A1
申请日:
2014.12.19
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Disclosed are novel substituted amino triazoles of Formula (I), and pharmaceutically acceptable salts thereof. The compounds of Formula (I) are inhibitors of Acidic mammalian chitinase (AMCase) and are useful, in a non-limiting example, for treating asthma. Also provided are pharmaceutical compositions containing at least one compound of the present invention, or a pharmaceutically acceptable salt, hydrate or solvate thereof, and at least one pharmaceutically acceptable carrier, solvent, adjuvant or diluent, and methods of using such compounds and/or compositions to treat asthma and/or to monitor asthma treatment.
