COMPOSITIONS AND METHODS TARGETING COMPLEMENT COMPONENT 3 FOR INHIBITING TUMOR GROWTH

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专利权人:

The Broad Institute, Inc.;The Brigham and Women's Hospital, Inc.;Massachusetts Institute of Technology

发明人:

Aviv Regev,Ana Carrizosa Anderson,Ayshwarya Subramanian,Orit Rozenblatt-Rosen

申请号：

US16622636

公开号：

US20200102386A1

申请日:

2018.06.14

申请国别(地区):

US

年份:

2020

代理人:

摘要：

This invention relates generally to compositions and methods for modulating complement component 3 (C3) activity or expression to treat, control or otherwise influence tumors and tissues, including cells and cell types of the tumors and tissues, and malignant, microenvironmental, or immunologic states of the tumor cells and tissues. The invention also relates to methods of diagnosing, prognosing and/or staging of tumors, tissues and cells.

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