Kristie Grove Bridges;Lisa-Anne Whittemore;Tejvir S. Khurana;Geertruida M. Veldman;Neil M. Wolfman;William J. Dunham;Mary L. Bouxsein;Monique V. Davies;Denise O'Hara
发明人:
Jane Aghajanian,Neil M. Wolfman,Denise O'Hara,Monique V. Davies,Geertruida M. Veldman,Kristie Grove Bridges,Lisa-Anne Whittemore,Tejvir S. Khurana,Mary L. Bouxsein,Denise OHara
申请号:
US13346042
公开号:
US08710202B2
申请日:
2012.01.09
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), including antibody fragments, which inhibit GDF-8 activity in vitro and in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle, bone, or insulin metabolism.