Solid forms comprising (1E, 4E)-2-amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo(b)azepine-4-carboxamide, compositions thereof, and uses thereof
Man, Hon-Wah,Fitzpatrick, Timothy D.,Frank, Anthony,Li, Ying,Lu, Xiaoling,Beauchamps, Marie G.,Ferretti, Antonio C.
申请号:
AU2015362720
公开号:
AU2015362720A1
申请日:
2015.12.15
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Provided herein are compositions including the crystalline forms of (IE, 4E)-2- amino-N,N-dipropyl -8-(4-(pyrrol i dine-l -carbonyl) phenyl)-3H-benzo[b]azepine-4-carboxamide ("Compound A"), methods of making the crystalline forms, and methods of using the crystalline forms for the treatment of diseases, including, for example, cancer. Provided herein are crystalline forms of the compound having formula (I). ((1E,4E)-2-amino-N;N-dipropyl-8-(4-(pyrrolidine- 1 -carbonyl)phenyl)-3Hbenzo[b]azepine-4-carboxamide ("Compound A")). The crystalline form can be an unsolvated or solvated crystalline form of the compound of formula (I).