Li Chen,Fariborz Firooznia,Paul Gillespie,Yun He,Tai-An Lin,Sung-Sau So,HongYing Yun,Zhenshan Zhang
申请号：
US13342150
公开号：
US08420675B2
申请日:
2012.01.02
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention is concerned with the compounds of formula I:and pharmaceutically acceptable salts and esters thereof, wherein Q, W, X, R1—R5 and n are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
