Paul J. Hergenrother,Karson S. Putt,Quinn P. Peterson,Valerie Fako
申请号:
US13087595
公开号:
US08592584B2
申请日:
2011.04.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds are disclosed in connection with modification of procaspases such as procaspase-3. In embodiments, compositions are capable of activation of procaspase-3.